High frequency 24-hour biological sampling

Monitoring fluctuating levels of body-chemistry is crucial for the assessment of biological rhythms - but traditionally difficult to do outside of a hospital setting. For the first time, we can sample biochemistry from subjects as they go about their everyday life (& undisturbed sleep)

U-RHYTHM samples provide New insights into what makes us tick

24-Hour dynamic testing in everyday life

For the 1st time the U-RHYTHM portable collection device collects biochemistry throughout a normal day and night with no discomfort or disruption to the wearer

Robust and reproducible sampling

U-RHYTHM exploits air-bubble fractionation technology to gather samples as frequently as every 10-20 minutes over 24-72 hours. Samples are analysed using state of the art LC-MS and proteomics techniques

minimally invasive microdialysis

U-RHYTHM extracts biochemistry from interstitial fluid - not blood. This means that U-RHYTHM is suitable for neonates, infants and critically ill patients that are vulnerable to infection and/or have a low circulating blood volume

Tissue-level bio-sampling

Only free (un-bound) biochemicals are extracted and analysed. This provides much better insight into bioactive molecules at a tissue level.